期刊文献+

HLA-Cw与疾病关系研究进展

下载PDF
导出
摘要 HLA-Cw为经典的HLA-I类基因,其编码产物的组织分布极为广泛,并且具有高度的多态性。HLA-Cw与K IR分子组成特异性信号传导系统,调节NK细胞活性,在机体抗感染免疫、肿瘤免疫、移植免疫中发挥重要作用。本文对HLA-Cw分子结构、基因多态性及与疾病关系研究进展作一综述。
出处 《微生物学免疫学进展》 2007年第1期76-78,共3页 Progress In Microbiology and Immunology
关键词 HLA-CW KIR 多态性
  • 相关文献

参考文献21

  • 1Cox ST,McWhinnie AJ,Robinson J,et al.Cloning and sequencing full length HLA-B and -C gene[J].Tissue Antigens 2003,61(1):20-48.
  • 2Swelsen WT,Voorter CE,van den Berg-Loonen EM.Polymorphism of intron 4 in HLA-A、-B and -C genes[J].Tissue Antigens 2003,61(6):475-483.
  • 3Kwon OJ,Hwang SH,Hur SS,et al.Novel HLA-Cw*01 allele,Cw*0111,identified by sequence-based typing[J].Tissue Antigens 2005,66(4):706-707.
  • 4Martin MP,Nelson G,Lee JH,et al.Cutting edge:susceptility to psoriatic arthritis:influence of actiating killer Ig-like receptor genes in the absence of specific HLA-Cw allels[J].J Immunol 2002,169(6):2818-2822.
  • 5Yen JH,Moore BE,Nakajima T,et al.Major hisrocompatibility complex class I recognizing receptoes are diseasenrisk genes in rheumatoid arthritis[J].J Exp Med 2001,193(10):1159-1167.
  • 6Flomenberg N,Baxter-Lowe LA,Confer D,et al.Impact of HLA Class Ⅰ and Ⅱ high resolution matching on outcomes of unrelated donor bone marrow transplantation:HLA-C mismatching is associated with a strong adverse effect on transplantation outcome[J].Blood 2004,104(7):1923-1930.
  • 7Tiercy JM,Passweg J,van Biezen A,et al.Isolated HLA-C mismatches in unrelated donor transplantation for CML[J].Bone Marrow Transplant 2004,34(3):249-255.
  • 8Moya-Quiles MR,MuroM,Torio A,et al.Human leukocyte antigen-C in short-and long-term liver graft acceptance[J].Liver Transpl 2003,9(3):218-227.
  • 9Saito S,Ota S,Seshimo H,et al.Platelet transfusion refractoriness caused by a mismatch in HLA-C antigens[J].Transfusion 2002,42(3):302-308.
  • 10Thio CL,Gao X,Goedert JJ,et al.HLA-Cw*04 and hepatitis C virus persistence[J].J Virol 2002,76(10):4792-4797.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部