吉林地区朝鲜族唾液酸性富含脯氨酸蛋白遗传多态性的研究

A STUDY OF GENETIC POLYMORPHISMS OF SALIVARY ACIDIC PROLINES IN KOREA POPULATION IN JILIN AREA

应用聚丙烯酸胺凝胶等电聚焦技术，调查了吉林地区226名朝鲜族个体唾液酸性富含脯氨酸蛋白二位点上共6种等位基因频率的分布：PRH1*1为0．0331，PRH1*2为0．2124，PRH1*4为0．7477，PRH1*6为0．0068；PRH2*1为0．7544，PRH2*2为0．2456。按Hardy－Weinberg法则进行吻合度检验，其观察值和期望值一致，并对吉林地区朝鲜族与其它地区人群酸性富含脯氨酸蛋白等位基因的差异性做了比较。PRH1和PRH2在吉林延边地区朝鲜族的个人识别能力分别为0.58和0．53，两者总鉴别机率为0．80；PRH1和PRH2的非父排除率为0．1875和0．1510，两者总非父排除率为0．3102。

The distribution of salivary acidic proline-rich proteins (APRPs ) phenotypes were studied using the ultra-thin polyacrylamide gel isoelectric focusing (PAGIEF ) technique in 226 parotid saliva sam-ples collected at random from Korea population in Jilin area. The gene frequencies were as follows:PRH1 *1 = 0.0331, PRH1 * 2 = 0. 2124,PRH1 * 4 = 0. 7477,PRH1* 6 =0.0068; PRH2 * 1 =0. 7544, PRH 2 *2 = 0. 2456. The observed numbers of the phenotypes were agreement with the ex-pected number under the Hardy-Weinberg equilibrium. The gene frequencies among Jilin and other area were compared.