38例早发型子痫前期重度临床分析

Clinical Analysis of 38 Early on Set Severe Preeclampsia

目的探讨早发型子痫前期重度的治疗及母儿结局。方法对38例不同孕周的早发型子痫前期重度进行回顾性分析。根据发病孕周分成A组(孕周<28周)、B组(28周≤孕周<32周)、C组(32周≤孕周<34周)。结果B组期待治疗的时间显著长于其他两组(P<0.05);B组、C组分娩方式以剖宫产为主;三组间患者并发症发生率无显著差异(P>0.05);三组间新生儿窒息发生率及围生儿死亡率有显著差异(P<0.05),随着孕周延长而下降。结论早发型子痫前期重度新生儿窒息发生率和围生儿死亡率随发病孕周延长而降低,期待治疗过程中应严密检测母婴情况,适时选择合适的终止妊娠的方式。

Objective To study the treatment and the maternal and neonatal outcomes of early onset severe preeclampsia. Methods A retrospective study was carried out on 38 patients with early onset severe preeclampsia, They were divided into three groups according to their onset gestation ages： group A （〈 28 weeks）, group B （28-7 32 weeks） and group C （32-34 weeks）, Results The rates of complications declined along with the postponement of the onset gestation age, but there was no statistical significant difference among these three groups. The neonatal asphyxia rate and perinatal infant mortality of these three groups declined along with the postponement of gestation age, and there were statistical significant differences among these three groups （P〈 0.05）. Expectant treatment time of group B was significantly longer than that of the other two groups （P〈 0.05）, and cesarean section was a main method of pregnancy termination for the groups B and C, Conclusion The neonatal asphyxia rate and perinatal infant mortality of early onset severe preeclampsia declined along with the postponement of pathogenic week of gestation, During the expectant treatment, the situation of maternity and fetus should be closely monitored and in time pregnancy termination.