实施辅助生殖技术后27例异位妊娠的临床分析

Ectopic pregnancy conceived with assisted reproductive technology（ART） - clinical analysis of 27 cases

目的探讨实施辅助生殖技术患者发生异位妊娠的危险因素、发生部位、预防措施、诊断和治疗。方法回顾性分析接受辅助生殖技术后303个临床妊娠患者的临床病例资料。结果303例实施辅助生殖技术后发生异位妊娠27例，发生率为8.9％，输卵管因素不孕患者异位妊娠发生率为10.6％，其中输卵管积水及有输卵管手术史的患者异位妊娠发生率分别为19.3％、13．0％。结论实施辅助生殖技术后异位妊娠的发生率与输卵管所致不孕有关，妊娠早期动态监测β-HCG和超声检查，有利于异住妊娠的早期诊治，可降低并发症的发生率。

Objective To study the risk factors,implantation sites,prevention methods and clinical manifestation for ectopic pregnancy（EP） conceived with ART. Methods A retrospective study of ectopic pregnancies among 303 pregnancies conceived with ART in Reproductive Medical Centre between January 2005 and March 2006. Results 27 of 303 pregnancies conceived with ART had ectopic pregnancies . The rate of EP was 8, 9%. The rates of EP in tubal infertility women,women who had hydrosalpinx, and women who had tubal surgery were 10. 6%, 19. 3 and 13.0%. Tubal infertility was associated with the incidence of EP. Conclusion The risk factor for ectopic pregnancy conceived with ART is tubule infertility. Dynamic observation of β-HCG and examination of transvaginal ultrasound during early trimester of pregnancy can benefit the early diagnosis and treatment of EP to decrease the incidence of implications.