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RNAi技术及其应用 被引量:2

RNAi technology and its application
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摘要 RNAi技术是指向特异的靶基因中导入双链RNA从而导致靶基因沉默的一种新技术.RNAi在调节转录后的基因表达水平方面有其独特的作用特点,随着研究的深入,具有广阔的应用前景.用RNAi技术调节基因表达在对不同生物基因功能的研究中已广泛应用.文中简要综述了RNAi技术的研究历史、研究进展和应用前景. RNAi technology is a novel technology which guides particular target gene to double - stranded RNA, resulting in target gene silence. As a new and developing experimental technique, the technique has particular function in regulating gene expression at post- transcription level. And has a wide spreading application future as more work spending in its developing. It's quite pel~,la~ to analyze functions of genes from different organism through regulating gene expressing with RNAi technology. This paper gives a brief overview on the history and the present achievement of RNAi technology study, and the future of its application as well.
作者 陈燕飞
出处 《韶关学院学报》 2006年第12期87-90,98,共5页 Journal of Shaoguan University
关键词 RNA干扰 双链干扰RNA 双链RNA DICER RNAi siRNA dsRNA Dicer
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  • 1胡新立,尚克刚.6个小鼠ES细胞系的建立和鉴定[J].北京大学学报(自然科学版),1996,32(2):248-253. 被引量:41
  • 2[1]Rander ES et al.Nature,2001;409:860
  • 3[2]Fire A et al.Nature,1998;391:806
  • 4[3]Waterhouse PM et al.Proc Natl Acad Sci USA,1998;95:13959
  • 5[4]Cogoni C et al.Nature,1999;399:166
  • 6[5]Ngo H et al.Proc Natl Acad Sci USA,1998;95:14687
  • 7[6]Sanchez-Alvarado A et al.Proc Natl Acad Sci USA,1999;96:5049
  • 8[7]Lohmann JU et al.Dev Biol,1999;214:211
  • 9[8]Kennerdel JR et al.Cell,1998;95:1017
  • 10[9]Li YX et al.Dev Biol,2000;217(2):394

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