摘要
目的:研究脱氢紫堇碱(DHC)对兔血小板中cAMP和cGMP含量的影响以探讨其抑制血小板聚集的作用机制。方法:应用放射免疫分析方法。结果:DHC显著增加兔血小板中cAMP的含量,而降低兔血小板中cGMP的含量。结论:DHC可能通过增加血小板中cAMP的含量和降低血小板中cGMP的含量而产生血小板抑制作用。
Objective： To study Effects of dehydrocorydaline（DHC） on cAMP and cGMP concentration in rabbit platelets in vitro. Methods： Radioimmunoassay method was used. Results： DHC increased cAMP concentration in rabbit platelets in vitro and decrease concentration in rabbit platelets. Conclusion： DHC may inhibit platelet aggregation through increasing cAMP and decreasing cGMP concentration in rabbit platelets.
出处
《中国民康医学》
2007年第6期165-165,180,共2页
Medical Journal of Chinese People’s Health
