干扰素α治疗慢性病毒性肝炎中干扰素受体调节的作用
被引量:2
摘要
目前,在慢性病毒性肝琰治疗中IFN具有重要作用,其抗病毒和免疫调节效应的发挥是通过与细胞表面特异性受体结合,从而激活一系列胞内信号转导机制。作为关键环节的受体,其活性并非一成不变,而是处于动态平衡中,既遵循一定的规律进行新陈代谢,同时又可受各种生理、药物、病理等因素的变化而调节。在IFN治疗过程中,IFN受体调节对治疗效果可产生重要影响。
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2007年第1期57-58,共2页
Chinese Journal of Infectious Diseases
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引证文献2
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