八元瓜环与N-苄基六次甲基四胺盐酸盐包结配合物的二维核磁共振研究

Study on inclusion complex of cucurbit[8]uril with N-benzylhexamethylene tetramine chloride by using 2D NMR techniques

利用1H NMR及二维核磁共振谱NOESY和ROESY,对八元瓜环(Q[8])与N-苄基六次甲基四胺盐酸盐(M)相互作用的模式进行考察,结果表明两者形成包结比为1∶2的主客体配合物,两个客体分子的苯环部分进入瓜环的腔内,而六次甲基四胺部分处于瓜环的两个端口。

The interaction model of the inclusion complex of cucurbit[ 8 ] uril （ Q [ 8 ] ） with N-benzyl-hexamethylene tetramine chloride （M） were assigned by using 2D NMR techniques such as NOESY and ROESY. The results revealed that two benzyl moieties of two guest M were included in the cavity of the host Q [ 8 ] to form a 1 ： 2 host to guest inclusion complex, the hexamethylene tetraminethe moieties of the guests were contained at the portals of the host Q [ 8 ].