经胸高频彩色多普勒超声评价高血压患者冠脉血流储备

Evaluation of coronary flow reserve by transthoracic high frequence color Doppler echocardiography in patients with hypertension

目的应用经胸高频彩色多普勒超声检测高血压患者的冠脉血流储备(CFR)功能。方法25例高血压左室肥厚组(LVH),23例高血压无左室肥厚组(no-LVH)和25例正常对照组(所有病例冠状动脉造影未见异常)。经静脉注射潘生丁,测量用药前、后心尖部心外膜冠状动脉的舒张期峰值血流速度,血流速度时间积分,计算其比值,作为冠脉血流储备指标。结果高血压患者无论有无LVH,CFR峰值速度比、CFR速度时间积分比均较对照组明显减低,差异显著(P<0.05,P<0.05)。结论原发性高血压患者均存在冠脉血流储备功能降低。

Objective Hypertension patient coronary flow reserve function（ CFR） is checked by transthoracic high frequence color Doppler echocardiography. Methods 25 subjects with essential hypertension not having left ventricular hypertrophy （ LVH ） and 25 normal subjects （all subjects were proved normal by coronary angiography }. Dipyridamole was injected through vein, before and after the injection, peak diastolic flow velocity and time velocity were measured, the ratio was calculated and used as an index of coronary flow reserve. Results Regardless of the hypertension patients having LVH or not,the CFR time velocity integrant and the CFR peak diastolic flow velocity were reduced more obviously than the comparing group （ P 〈0. 05, P 〈0. 05 ）. Conclusion Ammunition hypertension patients all have coronary reserve function reduction.