期刊文献+

内皮抑素及其对血管生成抑制作用的研究进展 被引量:1

下载PDF
导出
摘要 目的对内皮抑素的来源、表达、结构、作用机制以及其对血管生成的抑制作用研究进展作一综述。方法对近几年的相关资料进行总结、归纳。结果与结论国内外对于内皮抑素对各种肿瘤的抑制作用已有了大量的研究,经证实内皮抑素作为一类内源性血管生成抑制剂,对于各类肿瘤有较好的治疗作用,具有良好的应用前景。
出处 《中国药学杂志》 CAS CSCD 北大核心 2007年第5期329-332,共4页 Chinese Pharmaceutical Journal
基金 国家教育部博士点基金资助课题(20040422021)
  • 相关文献

参考文献9

二级参考文献76

  • 1John H, Preissner KT, Forssmann WG, et al. Novel glycoaylate form of human plasma endostatin and circulating endostatin-related fragments of collagen XV[J]. Biochemistry, 1999,38(32):10217-33.
  • 2Kerbel RS.A cacer therapy resistant to resistance.Nature,1997;390(6658) :335-336.
  • 3Ferrara N ,Davis-Smyth T.The biology of vascular endothelial growth factor.Endocr Rev.1997 Feb;18(1):4-25.
  • 4Hajitou A, Gignet C, Devy L, et al. The antitumoral effect d endostatin and angioetafin is associated with a down -regulation of vascular endothelial growth factor expression in tumor cells. FASEB J 2002 Nov;16(13) : 1802 - 4.
  • 5Folkman J. Tumor angiogenesis: therapuctic implication[J]. N Engt J Med, 1971,285:1182.
  • 6O'Beilly MS, Bodun T, Shing Y, et al. Eaxlosmtin: an endogenous inhibitor of angiogenesis and tumor growth [J].Cell, 1997,88(2):277-85.
  • 7Bodun T, Folknum J, Browder T, et al. Antiangiogenic therapy cx experimental cancer does not induce acquired drug resistance.Nature, 1997,390(6658) :404.
  • 8Nod Weidner Intra tumour microvessel density as a taugnosfic factor in cancer[J], Am J Pathol, 1995,147:9-19.
  • 9Gately S, Twardowski P, Stack MS. et al. Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin. Cancer Res .1996,156(21):4887-90.
  • 10Folkrnan J. Tumor angiogenesis and tissue factor. Nat Med. 1996 Feb;2002:167-8.

共引文献55

同被引文献7

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部