摘要
目的研究田基黄(Hypericum japonicum Thunb.)的化学成分。方法运用多种色谱技术对田基黄的化学成分进行系统研究,根据光谱数据鉴定化合物结构。结果分离鉴定了12个化合物,分别为:异巴西红厚壳素(Ⅰ),槲皮素(Ⅱ),山柰酚(Ⅲ),槲皮素-7-O-α-L-鼠李糖苷(Ⅳ),槲皮苷(Ⅴ),异槲皮苷(Ⅵ),槲皮素-3-O-β-D-葡萄糖醛酸苷(Ⅶ),田基黄双酮(Ⅷ),3,8″-biapigenin(Ⅸ),白桦酸(Ⅹ),豆甾醇(Ⅺ),豆甾醇-3-O-β-D-葡萄糖苷(Ⅻ)。结论化合物Ⅶ,Ⅸ,Ⅻ为首次从该植物中分离得到。
OBJECTIVE To investigate the chemical constituents of Hypericum japonicum. METHODS The compounds were separated by chromatography and their chemical structures were elucidated by means of MS, ^1 H-NMR and ^13C-NMR spectral methods, respectively. RESULTS Twelve compounds were isolated from the plant,they were identified as isojacareubin ( Ⅰ ) ,quercetin ( Ⅱ ), kaempferol ( Ⅲ ), quercetin-7-O-α-L-rhamnoside ( Ⅳ ), quercitrin ( quercetin-3-O-α-L-rhamnoside, Ⅴ ), isoquercitrin ( quercetin-3-O- β-D-glucoside, Ⅵ ), miguelianin ( quercetin-3-O-β-D-glucuronide,Ⅶ ), bijaponicaxanthone ( Ⅷ), 3,8"-biapigenin ( Ⅸ ), betulinic acid (Ⅹ) ,stigmasterol (Ⅺ) and stigmasterul-3-O-β-D-glucopyranoiside (Ⅻ). CONCLUSION Compound Ⅶ, Ⅸ and Ⅻ are isolated from this plant for the first time.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2007年第5期341-344,共4页
Chinese Pharmaceutical Journal
关键词
田基黄
化学成分
Hypericum japonicum
chemical constituents