Cu^(2+)对牙鲆肌肉抗氧化防御系统的影响

Effect of Cu^(2+) on the Antioxidative Defence in Muscle of Paralichthys olivaceus

将牙鲆(Paralichthys olivaceus)置于不同浓度的Cu2+溶液中10d,测定其肌肉中过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-PX)、超氧化物歧化酶(SOD)的活性。结果表明:随着Cu2+浓度的增高,CAT、SOD、GSH-PX的活性均表现为低浓度诱导,高浓度抑制;当处于低浓度Cu2+溶液中时,牙鲆肌肉中的SOD较CAT和GSH-PX敏感,因此其可作为水生生态系统中Cu2+低浓度暴露的一种生物检测指标。

The experiment was to study the effect of Cu^2＋ on the antioxidative defence system in muscle of Paralichthys olivaceus, such as the activities of CAT, SOD and GSH-PX. After 10 days＇ exposure experiment, the results showed that the activities of CAT, SOD and GSH-PX were inducted in low concentration of Cu^2＋ and inhibited in high concentration of Cu^2＋ . These results also suggested SOD was more sensitive to low concentration of Cu^2＋ than the others, and it could be served as bio-monitoring index of low concentration Cu^2＋ exposure in aquatic ecosystem.