芹菜籽黄酮类化学成分研究

Flavonoids from celery seed

目的:研究维药芹菜籽黄酮类化学成分。方法:采用聚酰胺、正相和反相硅胶柱色谱法分离纯化,波谱法进行结构鉴定。结果:从芹菜籽的乙醇提取物的正丁醇萃取部分分得5个化合物,其中4个为黄酮类化合物,其结构鉴定为木犀草素-3′-O-β-D-葡萄糖苷(luteolin-3′-O-β-D-glucopyranoside,1),木犀草素-7-O-β-D-葡萄糖苷(luteolin-7-O-β-D-glucopyranoside,2),香叶木素-7-O-β-D-葡萄糖苷(diosmetin-7-O-β-D-glucopyranoside,3),柯伊利素(chrysoeriol,4),豆甾醇-3-O-β-D-葡萄糖苷(stigmasterol-3-O-β-D-glucopyranoside,5)。结论:以上各化合物均为首次从该植物中分离得到。

AIM： To study the chemical constituents of celery seed. METHODS： Separation and purification were performed on polyamide, silica gel and ODS reverse phase gel column chromatography. Their structures were elucidated by means of spectral analysis. RESULTS： Five compounds were identified as luteolin-3＇-O-β-D-gluco- pyranoside （ 1 ）, luteolin-7-O-β-D-glucopyranoside （ 2 ） , diosmetin-7-O-β-D-glucopyranoside （ 3 ）, chrysoeriol （ 4 ）, stigmasterol-3-O-β-D-glucopyranoside（5 ）. CONCLUSION： All the compounds were isolated from this plant for the first time.