摘要
目的:观察а1a受体阻滞剂合用抗生素治疗慢性细菌性前列腺炎(cp)的疗效。探讨а1a受体阻滞剂在慢性前列腺综合症中的作用与机制。方法将95例慢性前列腺炎患者都随机分为两组,实验组(50例),口服а1a受体阻滞剂(盐酸坦索罗辛)及氧氟沙星。对照组(45例),只口服氧氟沙星,治疗5周。观察治疗前后尿动力学指标,前列腺液常规及前列腺炎症状评分的改变。结果а1a受体阻滞剂可有效地降低膀胱颈及前列腺的平滑肌张力,减少尿道阻力,缓解尿液前列腺返流,改善慢性前列腺炎患者的症状。
Purpose: To investigate the efficiency of a1a adrenoceptor blocker in treatment of Chronic Postatitis. Methods: 95 patients with chronic Prostatitis received either a1a adrenoceptor blocker (tamsulosin) combined with of loxasin or the latter alone for 5 weeks. Symptoms scores,urodynamic indexes and prostatic secretion examination were recorded before and after therapy. Result: There are were significant therapentic effects of tamsulosin cambined with of loxasin than that of loxasin alone in the treatment of chronic prosfatitis. Conclusion: a1a adrenoceptor blocker can decrease the intmurethral pressure,prevent urethroprostatic reflux, improve urinary symptoms of patients with chronic prostatitis.
出处
《医药世界》
2007年第2期33-34,共2页
Medicine World
关键词
前列腺炎
a1a
受体阻滞剂
尿动力学
Prostatitis
Adrenergicc alpha receptor blockaders
Urodynamics