慢性前列腺的药物治疗

目的:观察а1a受体阻滞剂合用抗生素治疗慢性细菌性前列腺炎(cp)的疗效。探讨а1a受体阻滞剂在慢性前列腺综合症中的作用与机制。方法将95例慢性前列腺炎患者都随机分为两组,实验组(50例),口服а1a受体阻滞剂(盐酸坦索罗辛)及氧氟沙星。对照组(45例),只口服氧氟沙星,治疗5周。观察治疗前后尿动力学指标,前列腺液常规及前列腺炎症状评分的改变。结果а1a受体阻滞剂可有效地降低膀胱颈及前列腺的平滑肌张力,减少尿道阻力,缓解尿液前列腺返流,改善慢性前列腺炎患者的症状。

Purpose： To investigate the efficiency of a1a adrenoceptor blocker in treatment of Chronic Postatitis. Methods： 95 patients with chronic Prostatitis received either a1a adrenoceptor blocker （tamsulosin） combined with of loxasin or the latter alone for 5 weeks. Symptoms scores,urodynamic indexes and prostatic secretion examination were recorded before and after therapy. Result： There are were significant therapentic effects of tamsulosin cambined with of loxasin than that of loxasin alone in the treatment of chronic prosfatitis. Conclusion： a1a adrenoceptor blocker can decrease the intmurethral pressure,prevent urethroprostatic reflux, improve urinary symptoms of patients with chronic prostatitis.