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Rho家族与肿瘤的侵袭转移的关系研究进展 被引量:3

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摘要 Rho全称Ras相似物(rashomologue),Rho家族成员在细胞的信号转导通路中起着重要作用。它在调节细胞骨架、细胞运动、细胞增殖、细胞凋亡、细胞转录、细胞转化、恶性肿瘤细胞的浸润和转移等方面发挥重要作用。近年来研究发现,Rho家族成员在多种肿瘤组织中呈高表达,并且与肿瘤的侵袭转移密切相关,提示Rho家族成员可能成为新的肿瘤标志物,在判断肿瘤的恶性程度及肿瘤的治疗方面发挥重要作用。
出处 《国际检验医学杂志》 CAS 2007年第3期217-218,221,共3页 International Journal of Laboratory Medicine
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