左旋布比卡因罗哌卡因混合苏芬太尼用于腹部术后镇痛的效果

The curative effect of laev-bupivacaine or ropivacaine compined with thero-fentanyl for patient-controlled epidural analgesia after abdominal operation

目的:研究0.15%左旋布比卡因与0.2%罗哌卡因用于腹部术后硬膜外镇痛的效果、对运动神经功能恢复的影响。方法:选择80例择期腹手术患者,ASAⅠ～Ⅱ级,采用随机双盲法分为两组:罗哌卡因组(组1,40例),左旋布比卡因组(组2,40例),两组术后分别采用0.2%罗哌卡因、0.15%左旋布比卡因复合苏芬太尼1μg/ml行硬膜外自控镇痛(PCEA),观察两组术后镇痛效果、运动阻滞程度和不良反应的发生情况。结果:两组术后视觉模拟评分(VAS)、Bromage评分及不良反应发生率均差异无显著性,接受0.2%罗哌卡因PCEA的患者术后活动能力恢复较早(P<0.05)。结论:0.2%罗哌卡因和0.15%左旋布比卡因复合苏芬太尼用于腹部术后硬膜外自控镇痛效果相同,罗哌卡因组的患者术后活动更早。

Objective ：To investigate the curative effect of laev-bupivacaine and ropivacaine for patient-controlled epidural analgesia（PCEA） after abdominal operation.Methods：With random and double blind methed,80 ASA Ⅰ-Ⅱ patients drafted for abdominal operation were divided into two groups,with 40 cases in each group.Group A was used with 0.2% ropivacaine combined with thero-fentany for PCEA,while group B with 0.15% laev-bupivacaine combined with thero-fentanyl.The curative effect of analgesia,the degree of motion block and occurrence of adverse reaction were observed respectively after operation.Results：There were no significant differences in both the scores of VAS and Bromage and the incidence of adverse reaction between two groups （P〉0.05）.Condusion：The curative effect of laev-bupivacaine combined with thero-fentanyl for PCEA is equal to that of ropivacaine combined with thero-fentanl.But the patients in group B can come to physical exercise early after operation.