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血红蛋白降解产物在脑出血后脑水肿形成中的作用

The Role of Hemoglobin Degradation Products in the Brain Edema Formation Mter Intracerebral Hemorrhage
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摘要 脑出血后，血肿内红细胞裂解释放出大量血红蛋白，血红蛋白降解为血红素和珠蛋白，血红素最终降解为铁、胆红素和CO，这些降解产物具有神经毒性并在脑水肿形成中起着重要作用。 The disruption of erythrocytes in hematoma after intracerebral hemorrhage （ICH） releases a great deal of hemoglobin, which degrades into heme and globin, the former will finally degrade into iron, bilirubin and CO. These degradation products have neurotoxicity and play an important role in the edema formation.
作者 孙智千 李作孝 刘广益
机构地区 泸州医学院附属医院神经内科
出处 《国际脑血管病杂志》 2007年第2期138-140,共3页 International Journal of Cerebrovascular Diseases
关键词 血红蛋白 脑水肿 脑出血 降解 血红素 珠蛋白 hemoglobin brain edema intracerebral hemorrhage
分类号 R74 [医药卫生—神经病学与精神病学]
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参考文献18

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国际脑血管病杂志
2007年 第2期

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