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慢性阻塞性肺疾病急性加重合并呼吸衰竭与尿崩症的关系

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摘要 目的了解慢性阻塞性肺疾病急性加重(AECOPD)时缺氧与尿崩症的关系。关系回顾性分析AECOPD合并呼吸衰竭患者和发生尿崩症患者入院时动脉血气情况及尿崩症患者缺氧后出现尿崩的时间及再次缺氧而出现尿崩的时间差别。结果所有AECOPD患者中,出现尿崩症的患者入院时动脉血氧分压降低明显,且再次缺氧至再次尿崩时间明显缩短。结论急性严重缺氧可引起下丘脑-垂体功能障碍,影响抗利尿激素(ADH)分泌,短时间内反复严重缺氧可致ADH分泌严重不足,甚至致永久性尿崩。
出处 《临床肺科杂志》 2007年第4期375-376,共2页 Journal of Clinical Pulmonary Medicine
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