酸性氧化电位水与戊二醛消毒内镜临床观察

Disinfection of Endoscope by EOW and Glutaraldehyde:A Clinical Observation

目的 了解酸性氧化电位水（EOW）和戊二醛用于临床无痛胃镜和肠镜消毒的效果、对人体危害及稳定性。方法 随机抽取门诊和住院患者做无痛胃镜和肠镜检查污染前后胃、肠镜，采用戊二醛消毒液为对照，比较两者的消毒效果、对人体的危害性及稳定性进行临床观察。结果 EOW消毒胃、肠镜对常见病原菌1min杀灭率为93．75％～98．22％、3min为99．30％～99．95％、5min为100．00％；戊二醛消毒胃、肠镜3min杀灭率为81．20％～89．29％、5min为90．38％～93．04％、10min为99．92％～99．96％；EOW对人体无过敏反应和黏膜刺激，但稳定性差；而戊二醛对人体均有黏膜刺激和个别过敏反应。结论 EOW3～5min可杀灭胃、肠镜检查中的病原菌，戊二醛消毒〉10min才能杀灭常见病原菌；EOW杀菌作用强，快捷、高效、安全，利于环保，但必须现生成现用；使用戊二醛必须注意个人防护。

OBJECTIVE To know the disinfection efficacy of electrolyzed oxidizing water （EOW） and glutaraldehyde on clinical used gastroscope and enteroscope in our hospital and to analyze their stability and probable harm. METHODS The gastroscope and enteroscope before and after use on randomly selected outpatients and inpatients were examined on their contamination, and the efficacy of EOW was compared with that of glutaraldehyde. RESULTS After using EOW and glutaraldehyde to disinfect the gastroscope and enteroscope the former showed that its killing rate on commonly encountered pathogens for 1 min was 93.75-98.22%, for 3 min was 81.20- 89. 29%, and for 5 min was 100.00% ; the latter showed that its killing rate for 3 min was 81.20-89. 29%, for 5 min was 90.38-93. 04%, and for 10 min was 99.92-99. 96%. EOW was non-irritative to mucosa, and didnrt cause allergic reaction, but its stability was poor. The glutaraldehyle could bring some side effects, such as some allergy, and mucosa stimulation. CONCLUSIONS It only needs 3-5 min for EOW to kill polluted bacteria on gastroscope and enteroscope to attain the disinfection eligibility, but glutaraldehyde needs more than 10 rain to get to the disinfection eligibility. The effect of EOW is strong, rapid, active and environment-safe, it is worthy of application, but it must be applied immediately as soon as possible after production. The use of glutaraldehyde must strengthen the measures of personal protection.