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聚唾液酸与唾液酸的研究进展 被引量：18

Recent progress in polysialic acid and sialic acid research
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摘要 唾液酸是一族神经氨酸(Neuraminic acid)的衍生物。聚唾液酸(Polysialic acid)是唾液酸(Sialic acid)单体以α-2,8或α-2,9键连接的直链同聚物,是一些哺乳动物细胞中糖蛋白的组成部分和少数几种细菌的胞外多糖组分。综述了唾液酸和聚唾液酸的结构、性质、生物学功能、生物合成和生产应用。 The term ＂sialic acid＂ is a group name for Neuraminic acid derivatives. Polysialic acid is a homopolymer of sialic acid in α-2,8 or α-2,9 ketosidic linkage, which is found only in a few animal glycoproteins and in certain bacterial intracellar polysaccharides, the structure, property, biological function, biosynthesis, production and application of sialic acid and polysialic acid were reviewed.
作者 吴剑荣 詹晓北 郑志永 贾薇
机构地区 江南大学工业生物技术教育部重点实验室
出处 《生物加工过程》 CAS CSCD 2007年第1期20-26,共7页 Chinese Journal of Bioprocess Engineering
基金 江苏省自然科学基金资助项目(BK99190)
关键词 唾液酸 聚唾液酸 神经黏附分子 唾液酸酶 缓释剂 sialic acid polysialic acid neural cell adhesion molecule neuraminidase controlled release
分类号 Q5 [生物学—生物化学]
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参考文献38

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二级参考文献34

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生物加工过程
2007年 第1期

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