毛细管电色谱柱及其固定相制备技术的进展

Advances in Column and Stationary Phase of Capillary Electrochromatography

毛细管电色谱结合了毛细管电泳的高分离效率和高效液相色谱的高选择性,因而在这几年受到了越来越多的关注。本文介绍了近期毛细管电色谱柱及其固定相制备方法和应用的进展。

Capillary electrochromatography （CEC） has attracted increasing interests in recent years. It combines the advantages of high efficiency of capillary electrophoresis （CE） with high selectivity of high performance liquid chromatography （ HPLC ）. CEC also has a double retention mechanism of both CE and HPLC and, therefore, is suitable for simultaneous separation and analysis of neutral and charged compounds. In this paper, the preparation methods for va- rious types of capillary columns for electrochromatography are reviewed in detail and their advantages and disadvantages are discussed.