摘要
目的探讨脑梗死患者血浆C反应蛋白(CRP)的动态变化与其病情之间的关系。方法对107例脑梗死患者发病后72 h内,第4-7天和第14天的血CRP进行测定,应用美国国立卫生研究院卒中量表(NIHSS)及Barthel指数(BI)记分法测定神经功能缺损评分。结果脑梗死后72 h血CRP浓度即开始升高,1周左右达高峰,至14 d时水平接近对照组水平,并发多脏器功能衰竭者CRP水平最高。结论血浆CRP是判断脑梗死病情轻重和预后的特异性指标,适时终止或减轻炎症反应损害,可以降低脑梗死的病死率及并发多脏器衰竭的危险。
Objective It is to discuss the relationship between the dynamic changes of plasma C reactive protein (CRP) in cerebral infarction patients and pathogenetic condition. Methods Plasma CRP of 107 cerebral infarction patients was determined in 72 h after onset, at the fourth to seventh day and at the fourteenth day. The neurologic impairment score was determined with NIHSS and BI method. Results Plasma CRP concentration had begun rising at 72 h after cerebral infarction, would reach the peak at about one week and would approach the level of control group at the fourteenth day. The CRP level of concurrence multiple organ failure was the highest. Conclusion Plasma CRP is specificity index of judging pathogenetic condition light and heavy press and prognosis of cerebral infarction. At the right moment stopping or lightening the inflam- matory reaction damage can lower the case fatality rate of cerebral infarction and the danger of concurrence multiple organ failure.
出处
《现代中西医结合杂志》
CAS
2007年第11期1458-1459,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
脑梗死
炎症反应
C反应蛋白
cerebral infarction
inflammatory reaction
C reactive protein