甲状腺疾病患者血清T_3、T_4、rT_3、TSH、TMA、TGA——RIA联合检测临床应用

CLINICAL APPLICATION OF COMBINED RIAs——T_3,T_4,rT_3,TSH,TMA,TGA SERUMAL TESTS FOR PATIENTS WITH THYROID DISORDERS

利用放射免疫测定方法(RIA),对502例正常人,84例甲亢病人及14例甲减病人联合测定 T_3、T_4、rT_3、TSH、TMA 和 TGA。甲亢病人 T_3、T_4、rT_3明显高于正常对照组,甲减病人明显降低。甲亢患者的血清 TMA 和 TGA 增高或正常(多见增高),TMA 阳性率均高于 TGA。甲减病人中 TSH 升高或正常是鉴别原发性甲减和继发性甲减的寸靠依据。联合使用上述6项检测指标综合分析有助于甲状腺疾病的鉴别诊断。

We analysed the RIA results of T_3,T_4,ΥT_3,TSH,TMA and TGA in 502 normal persons,84 cases of thyroidism and 14 cases of hypothyroidism.The results of the above 6 tests fell in the normal range while T_3,T_4,and ΥT_3 were remarkably higher in hypothyroidism.TMA and TGA were normal or higher(often higher)in both cases,the TMA positive rate being higher than that of TGA.Normal or higher TSH in patients with hypothyroidism was a reliable index in the differential diagnosis of primary and/or secondary hypothyroidism.It was evident that a comprehensive analysis of the results of the 6 above-mentioned tests would be helpful for the differential diagnosis of thyroid disorders.