2SIMEONORA PP,GALLUCCI RM,HULDERMAN T,et al.The role of tumor necrosis factor-alpha in liver toxicity,inflammation and fibrosis induced by carbon tetrachloride[J].Toxicol Appl Pharmacol,2001,177 (2):112-120.
3RODRIGUEZ L,CERBON AJ,MUNOZ ML.Effects of colchicines and colchiceine in a biochemical model of liver injury and fibrosis[J].Arch Med Res,1998,29 (2):109-116.
9JIANG Z,YOU DY,CHEN XC,et al.Monitoring of serum markers for fibrosis during CCI4-induced liver damage.Effects of anti-fibrotic agents[J].J Hepatol,1992,16(3):282-9.
10VENDEMIALE G,GRATTAGLIANO I,CARUSO M L,et al.Increased oxidative stress in dimethylnitrosamine-induced liver fibrosis in the rat:effect of N-acetylcysteine and interfere on-alpha[J].Toxicol Appl Pharma2col,2001,175(2):130-139.
2[1]Jamall I S,Finelli V N,Quehee S S.A simple method to determine nanogram levels of 4-hydroxy-proline in biological tissues.Anal Biochem,1981,112:70.
3[2]Nakayama Y,Takahara T,Miyabayashi C,et al.Ultrastructural locali-zation of type Ⅳ collagen and laminin in the disse spase of rat liver with carbon tetrachloride induced fibrosis.Liver,1991,11:260.
4[3]Rockey D C,Weisiger R A.Endothelin induced contractility of stellation of portal pressure and resistance.Hepatology,1996,24:233.
5[4]Pinzani M,Milani S,De-Franco R, et al.Endothrlin I is over expressed in human cirrhotic liver and exerts multiple effects on activiated hepatic stellate cells.Gastroenterology,1996,110:534
6[5]Fredman S L.The cellular basis of hepatic fibrosis:Mechanisms and treatment strategies. N Engl J Med,1993,328:1828.
7李健军，中华医学杂志，1988年，68卷，372页
8郑少雄，中华医学检验杂志，1986年，31卷，36页
9侯建存，免疫化学技术，1980年
10Krahenbuhl S, Weber FL Jr, Brass EP. Decreased hepatic glycogen content and accelerated response to starvation in rats with carbon tetrachloride-induced cirrhosis. Hepatology 1991;14:1189-1195.
