急性心肌梗死并发心房颤动持续时间及预后关系研究

Prognosis of patients in relation to duration of new-onset atrial fibrillation following acute myocardial infarction

目的探讨急性心肌梗死(AMI)并发心房颤动(AF)的持续时间对其预后的影响。方法用ROC分析确定房颤持续时间对预后影响的时间点。在298例AMI并发AF的患者中,对比心房颤动持续时间AF<7小时130例与AF≥7小时168例患者的相关临床资料,并进行统计分析。结果急性心肌梗死并发心房颤动持续时间AF≥7小时患者特点是高龄、严重的心衰。且住院期间心衰、心源性休克、梗死后心绞痛及死亡的发生率显著高于心房颤动持续时间AF<7小时患者(P<0.05)。结论AF持续时间≥7小时可能是AMI并发AF患者不良预后的独立危险因素。

Objective The duration of new-onset atrial fibrillation （AF） following the acute myocardial infarction （A-MI） was evaluated as well as its relation to prognosis. Methods A total of 298 consecutive patients with AF following AMI were examined and patients with AF〈7 h（n=130） were compared to those with AF≥7h in duration（n = 168）. Receiver Operating Characteristic analysis was performed to identify the most useful AF duration cut-off level. Results Patients with AF≥ were older and had more advanced heart failure than patients with AF〈7 h. Patients with AF≥7 had higher in hospital mortality（P〈0.05）. Conclusion New-onset AF≥7 h in duration following the AMI independently predicts poor prognosis.