摘要
细胞周期调控异常会导致肿瘤的发生和发展,Cyclin D1是细胞周期的重要调控元件之一,与肝癌发生、进展及预后关系密切。本文就Cyclin D1的结构、功能、作用机制、肝癌组织中Cyclin D1及其相关基因研究的进展情况予以综述。
The dysfunction of cell cycle regulation wottld resttlt in the occurrence and development of tumor. Cyclin D1 was an important regulatory element in cell cycle, which correlated with occurrence, development and prognosis of liver cancer. In this paper, the structure, function and mechanism of Cyclin D1 were reviewed, while advancement of research about Cyclin D1 and related genes in liver cancer tissue were also summarized.
出处
《现代生物医学进展》
CAS
2007年第1期131-134,共4页
Progress in Modern Biomedicine
基金
国家自然科学基金
项目编号:30271576
30400582
30672574
教育部高等学校博士学科点专项基金
上海市卫生局科研基金
项目编号:2004Q009J
上海市教委基金
项目编号:04CB04。