电镜对卵巢粘液上皮肿瘤的诊断价值

Diagnostic Value or Electron Microscopy on Ovarian Mucinous Epithelial Tumors

研究卵巢粘液上皮肿瘤(OMET)的电镜诊断特征。对20例OMET进行电镜观察,并与光镜对照。发现20例OMET中,8例良性,5例交界性和7例恶性。光镜、电镜和临床表现大致符合,诊断符合率为17/20(85％)。在良性组内有2例电镜可见分化不良细胞及癌组织特征,临床有腹膜种植转移,1例死于癌晚期(2年内)。交界组内,1例电镜下见到癌组织特征,术后10个月复发。结论指出电镜超微结构病理学,特别是细胞粘合力,对卵巢粘液上皮肿瘤的种植转移、早期诊断和预后有重要参考价值。

To investigate the diagnostic features of electron microscopy in ovarian mucinous epithelial tumors (OMET),20 cases of OMET were observed with electron microscopy and light microscopy. The results were as following: 8 cases were benign ; 5 cases bordline ; and 7 ncases malignant. Coincident rate of light microscopy, electron microscopy, clinic expression was 17/20 (85%). Character of undifferentiation was found with electron microscopy. In benighn group, 2 cases had metastasis of peritoneal implants. One died from advanced cancer after 2 years. Character of cancer tissue was found in one case of borderline group, and recurred after 10 mounths of postoperation. The paper indicates ultrastructural feature , especially, of cell adhesion has an important value for implant metastasis, primary diagnosis and prognosis of OMET.