家兔实验性脊髓空洞症脑室系统变化的定量分析

Quantitative Analysis on Brain Ventricles of Experimental syringomyelia in Rabbit

为了进一步探讨脊髓空洞症的病因,应用小脑延髓池注入高岭土方法,造成家兔实验性脊髓空洞症模型,并用电子计算机图像分析系统测试其脑室系统不同水平截面积的变化。结果:脊髓空洞症模型动物脑室系统明显扩张,呈脑积水改变,且脑室扩张的程度一般与脊髓空洞的大小呈平行关系。结论:高岭土阻塞第四脑室出口,以及继发性蛛网膜炎加重脑脊液循环通路阻塞,其引起的脑脊液流体动力学紊乱是模型动物形成脊髓空洞症的主要原因。

To further study the cause of syringmyelia , experimental rabbit model of the disease was established by injection of cisterna magra kaolin. The area of brain ventricles at different section was measured by a computer imaging system. The brain ventricular system in the model was observed to be enlarged in a state of cephalus, and the enlargement was parallell to severity of syringomyelia. The obstruction of fourth ventricullar outlet by kaolin granules and secondary arachnoiditits, influencing the hydrokinetics were the principal causes of syringonmyella in the animal model.