颈动脉粥样硬化与动脉血压的相关性分析

The relationship between arterial blood pressure and carotid atherosclerosis.

目的 将临床常用的血压测定和外周动脉超声技术相结合，研究颈动脉粥样硬化与动脉血压的相关性。方法 对所有入选病例行颈动脉超声检查，并根据颈总动脉内．中膜厚度（IMT）分为正常对照组（IMT〈0．10 mm）和颈动脉斑块组（IMT≥ 0．10 mm）。并测量血压、血糖、血脂、身高和体重。结果 颈动脉斑块组与正常对照组比较，反映动脉弹性的脉压（PP）、脉压指数（PI）、平均管壁张力（CWS）差异有显著性（P〈0．01）；反映早期动脉粥样硬化的IMT与CWS及收缩压的相关程度最高（标准回归系数为-0．668和0．256）。结论 粥样硬化病变可致动脉弹性下降；早期动脉粥样硬化与中央动脉弹性下降有关。

Objective To study the relationship between arterial blood pressure and carotid atherosclerosis by use of commonly used pressure measurement in combination with peripheral carotid uhrasonograph. Methods All selected cases were divided into control group （ IMT 〈 0. 10mm ） and carotid atherosclerotic plaques group （IMT≥0.10 mm） according to carotid Intima-media thickness（IMT） after they underwent peripheral carotid ultrasonograph. Blood pressure, blood glucose and lipid, height and weight were measured. Results The difference of pulse pressure（PP） ,pulse index（P I） and CWS reflecting arterial flexibility was different between the two groups （P 〈0.01 ）. IMT which could reflect early atherosclerosis was highly correlated with CWS and systolic pressure （ OR = - 0.668 and 0. 256）. Conclusion Atherosclerosis might lead to the reduce in arterial flexibility. Early atherosclerosis is related to the reduce of flexiility of central artery.