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过敏性哮喘血浆可溶性白介素2受体与嗜酸性细胞、嗜碱性细胞、总IgE关系的研究 被引量:2

Relationships between Plasma SIL-2R and Eosinophil Count,Basophil Count,IgE in Allergic Asthma
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摘要 30例过敏性哮喘患者和24例正常人分别被检测了血浆可溶性白介素2受体(SIL-2R)、IgE和全血嗜酸性细胞、嗜碱性细胞值,可观察到哮喘组SIL-2R平均值为2320pg/mL,明显高于正常组的1760.94pg/mL)(P<0.05),表明哮喘组T细胞呈活化状况。哮喘组的嗜酸性细胞、嗜碱性细胞、IgE增高的百分率分别为63.33%(19/30)、66.67%(20/30)和36.67%(11/30),均明显高于正常组的4.17%(1/24).哮喘组中有8例SIL-2R值大于3000pg/mL,其中4例(50%)嗜酸性细胞、IgE2项检测及嗜酸性细胞、IgE、嗜碱性细胞3项检测均增高,且病情较重,而在SIL-2R≤3000pg/mL的22例中,其2项、3项检测同时增高者仅3例(13.64%),2组差异显著(P<0.05),提示血浆SIL-2R的检测对研究哮喘的发病机理和反映病情严重状况均有意义。 Plasma SIL-2R,blood eosinophil count, basophil count were detected in 30 allergic asthmatics,as well as in 24 healthy controls withoout asthma. It was showed that the mean level of SIL-2R in asthmatics was 2320 pg/mL,being much higher than that of 1760. 94 pg/mL in the normal control group (P<0. 05). It indicated that the T lymphocyte was activated in allergic asthma. The elevation rate of eosinophil count, basophil count and IgE was 63. 33% (19/30), 66. 67% (20/30), and 36. 67% (11/30), respectively in asthma group, being much higher than 4. 17%(1/24), 4. 17% (1/24 )and 4. 17%(1/24), respectirely in the control group (P<0. 05). There were 8 asthmatics with SIL-2R>3000 pg/mL,and among them 4 cases (50%) showed both elevation of eosinophil count and IgE,or elevation of three items including eosinophil count,basophil count,IgE, but only 3 cases showed the same elevation in 22 asthmatics with SIL-2R≤3000 pg/mL. There is significant difference between these two groups (P<0. 05).
出处 《标记免疫分析与临床》 CAS 1996年第4期200-202,共3页 Labeled Immunoassays and Clinical Medicine
关键词 哮喘 T细胞 过敏性哮喘 SIL-2R IgE SIL-2R Asthma Tlymphocyts
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同被引文献8

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