麻疹IgM抗体的检测和麻疹误诊分析

DETECTION OF MEASLES IgM ANTIBODY AND ANALYSIS ON MEASLES MISSDIAGNOSIS

对１９８８年以来收集的部分疑似麻疹病例血清，采用麻疹和风疹ｌｇＭ抗体捕捉ＥＭ法进行检测．结果在 １５９４份疑似麻疹病例的血清中，麻疹ＩｇＭ抗体阳性者９１４份，阳性率为 ５７．３％。对 １７２份麻疹ＩｇＭ抗体阴性的血清检测了风疹ＩｇＭ抗体，发现３９份阳性，阳性率２２、７％。说明疑似麻疹的病例中有一部分是风疹病例，从而为科学鉴别麻疹与风疹、及时控制麻疹疫情提供了依据。

Sera from suspected measles cases were collected since 1988 and they were assayed for measles IgM and rubella IgM by antibody-captured EIA. Of l,594 measles suspected serum samples collec- ted, 914 were measles IgM positive, the positive rate was 57.3%. Of 172 measles IgM negative sera, 39 were rubella IgM positive, the positive rate are 22.7% The results shoed that a number of mea sles suspected cases un in fact infected by rubella virus. To differentiate rubella from measles pro- vides an scientific basis for measles control.