血管内皮生长因子受体3抗体用于乳腺癌微淋巴管密度检测
摘要
作者采用免疫组化法,以血管内皮生长因子受体-3(vascular endothelial growth factor receptor-3 ,VEGFR-3,又称FLT-4)为标记物,检测乳腺癌组织内微淋巴管密度(microlymphatic density,MID),研究其与增殖期细胞核抗原( proliferating cell nuclear antigen, PCNA)蛋白及临床病理因素之间的相关性。
出处
《南京医科大学学报(自然科学版)》
CAS
CSCD
北大核心
2007年第3期290-291,共2页
Journal of Nanjing Medical University(Natural Sciences)
参考文献10
-
1许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量:1365
-
2Skobe M,Hawighorst T,Jackson DG,et al.Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis[J].Nat Med,2001,7(2):192-198
-
3Stacker SA,Caesar C,Baldwin ME,et al.VEGFD promotes the metastatic spread of tumor cells via the lymphatics[J].Nat Med,2001,7(2):186-191
-
4Kaipainen A,Korhonen J,Mustonen T,et al.Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development[J].Proc Natl Acad Sci USA,1995,92:3566-3570
-
5刘晓,范萍,王水,武正炎.血管内皮生长因子及其受体蛋白在乳腺癌组织中的表达及意义[J].南京医科大学学报(自然科学版),2005,25(11):777-779. 被引量:3
-
6Nakamura Y,Yasuoka H,Tsujimoto M,et al.Lymph vessel density correlates with nodal status,VEGF-C expression,and prognosis in breast cancer[J].Breast Cancer Res Treat,2005,91(2):125-132
-
7Jussila L,Valtola R,Partanen TA,et al.Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3[J].Cancer Res,1998,58(8):1599-1604
-
8Schoppmann SF,Bayer G,Aumayr K,et al.Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer[J].Ann Surg,2004,240(2):306-312
-
9Longatto Filho A,Martins A,Costa SM,et al.VEGFR-3 expression in breast cancer tissue is not restricted to lymphatic vessels[J].Pathol Res Pract,2005,201(2):93-99
-
10Jacquemier J,Mathoulin-Portier MP,Valtola R,et al.Prognosis of breast-carcinoma lymphagenesis evaluated by immunohistochemical investigation of vascular-endothelial-growth-factor receptor 3[J].Int J Cancer,2000,89(1):69-73
二级参考文献13
-
1许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量:1365
-
2赵彤,朱梅刚,黄宗义,张亚历,张素娟,李梅芳.肺癌癌基因蛋白产物同步检测的对比分析[J].癌症,1995,14(1):13-15. 被引量:54
-
3谷化平,冯和平,徐志勇,苏红.免疫组化在恶性黑色素瘤诊断中的作用[J].中国肿瘤临床,1996,23(8):599-600. 被引量:4
-
4Toi M, Hoshina S, Takayanagi T, et al. Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer[J]. Jpn J Cancer Res, 1994,85(10):1045-1049.
-
5Brown LF, Guidi AJ, Schnitt SJ, et al. Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast [J]. Clin Cancer Res,1999,5(5): 1041-1056.
-
6Lee AH, Dublin EA, Bobrow LG, et al. Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis[J]. J Pathol, 1998,185(4):394-401.
-
7Linderholm BK, Lindh B, Beckman L, et al. Prognostic correlation of basic fibroblast growth factor and vascular endothelial growth factor in 1307 primary breast cancers[J ]. Clin Breast Cancer, 2003,4(5): 340-347.
-
8Manders P, Sweep FC, Tjan-Heijnen VC, et al. Vascular endothelial growth factor independently predicts the efficacy of postoperative radiotherapy in node-negative breast cancer patients [J ]. Clin Cancer Res, 2003,9(17):6363-6370.
-
9Foekens JA, Peters HA, Grebenchtchikov N, et al. High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer [ J ]. Cancer Res, 2001,61 (14): 5407-5414.
-
10Ludovini V, Sidoni A, Pistola L, et al. Evaluation of the prognostic role of vascular endothelial growth factor and microvessel density in stages Ⅰ and Ⅱ breast cancer patients [ J ]. Breast Cancer Res Treat, 2003,81 (2): 159-168.
共引文献1366
-
1刘晓菲,王圆圆,宿琦琦,李静蔚,陈翰翰,张丽美.益气和营法调控肉芽肿性乳腺炎IL-6、IL-1β、IFN-γ免疫失衡机制[J].世界科学技术-中医药现代化,2022,24(9):3442-3448. 被引量:2
-
2李晓枫,刘展华.SREBP2在原发性肝癌中的表达水平与临床病理特征及预后的关系[J].热带医学杂志,2019,19(10):1201-1204. 被引量:6
-
3郑艳敏,刘积平,周小嫔,赵红艳,于美娜,牛海艳.β-catenin与Lgr5在胃癌进程中的表达及其意义[J].武警医学,2021,32(10):836-839. 被引量:1
-
4李德锋,罗爱华,罗泊涛,姜汉国.Vimentin、ER、CEA、PR以及P16在子宫内膜样腺癌与宫颈腺癌中的表达研究及差异性分析[J].名医,2020(5):7-8.
-
5杨涵,黄学惠,邓继红,张雯,杨廷仙.骨桥蛋白(OPN)与卵巢上皮性肿瘤[J].世界最新医学信息文摘,2020(48):3-4.
-
6胡波,贾永华,李小薇,王波,毛利民,吕申,应丽.碱性纤维母细胞生长因子(bFGF)的检测有助于判断肉瘤恶性程度[J].大连医科大学学报,2001,23(1):23-25. 被引量:4
-
7苗芳,李劲松.EZH2和Ki-67在胃癌中的表达及其临床意义[J].泰山医学院学报,2008,29(2):87-89. 被引量:6
-
8戴志远,蒋创,谢芳.p53蛋白在卵巢上皮肿瘤组织中的表达及其临床意义[J].苏州大学学报(医学版),2008,28(1):68-69.
-
9朱吉海,达嘎,李勇,武建英.凝血栓蛋白-1及P53对非小细胞肺癌组织血管新生的影响及其意义[J].青海医药杂志,2008,38(3):4-8.
-
10黄健,李小宁,陈永井,赵英伟,张学光.人结肠直肠癌组织中B7-H1的表达及其临床意义[J].现代免疫学,2008,28(5):358-361. 被引量:2
-
1周汝武,杨怀英,张桂芹,司庆华.乳腺良性病变误诊为乳腺癌25例分析[J].齐鲁肿瘤杂志,1997,4(1):54-54.
-
2汪玉,冯晓冬,南进军,魏建彬.EGFR在乳腺浸润性导管癌中的表达及其临床意义分析[J].临床医学工程,2016,23(4):471-472. 被引量:3
-
3王治伟,熊裕民,赵子龙.miR-574-5p在乳腺癌患者血清中的水平及与临床病理特征的关系[J].检验医学与临床,2016,13(21):3011-3013. 被引量:5
-
4高明,邓跃华,刘弋,陈飞.原发性十二指肠癌临床特点及其微血管密度检测的意义[J].中国现代医学杂志,2007,17(15):1887-1889. 被引量:4
-
5李大鹏,韩小弟,张力伟.p53基因碱性成纤维生长因子微血管密度检测用于判断垂体腺瘤侵袭性及评估预后的临床价值[J].中国肿瘤临床与康复,2015,22(1):25-28. 被引量:4
-
6胡赟宏,苏光启,叶古祥.乳腺癌患者血管内皮生长因子与微血管密度检测的临床意义[J].中国综合临床,2003,19(4):351-352. 被引量:1
-
7陈骏,孙振柱.乳腺癌中血管内皮生长因子A表达和微血管密度检测的临床意义[J].临床与实验病理学杂志,2006,22(1):102-104. 被引量:3
-
8王静,李秋芳,杨继要,杨霄鹏,吴逸明,吴拥军.非小细胞肺癌组织中PTEN、P53蛋白及微血管密度检测[J].郑州大学学报(医学版),2006,41(2):266-268. 被引量:6
-
9韩斌,梁冰,王广田,庞志刚,孙培春.肝细胞癌组织中碱性成纤维细胞生长因子和微血管密度检测[J].郑州大学学报(医学版),2006,41(4):704-706. 被引量:5
-
10廖勇,阎洪涛,王东,龚百生,邹建华,杨红,陈照祥.膀胱移行细胞癌中微血管密度检测的临床意义[J].现代泌尿外科杂志,2006,11(2):81-82. 被引量:3