含磷单体改性聚乳酸生物材料的合成与表征

Synthesis and characterization of biodegradable material polylactic acid modified by phosphorus monomer

以二氯磷酸苯酯(PDP)为含磷单体,通过直接聚合法改性生物降解材料聚乳酸,利用傅里叶变换红外光谱、核磁共振氢谱与磷谱、差示扫描量热与凝胶渗透色谱等表征了改性产物,探讨了聚合方式、不同原料配比等条件对改性材料重均分子量(Mw)的影响。当外消旋乳酸、乙二醇、PDP摩尔比为20:1:1时,在160℃、70 Pa条件下ZnO(质量分数0．5％)催化熔融聚合8 h,产物的帆高达28 000,相对分子质量分布为1．07。

A kind of biodegradable material polylactic acid （PLA） was modified via direct polymerization with phenyl dichlorophosphate （PDP） as phosphorus monomer. The modified PLA was systematically characterized by Fourier transform infrared spectroscopy, hydrogen Spectrum and phosphorous spectrum of nuclear magnetic resonance, differential scanning calorimetry and gel permeation chromatography . The influences of synthetic conditions, such as polymerization process and molar ratio of feedstock, on relative weight average molecular could reach 28,000 and 1.07, respectively, when the melt polymerization was carried on for 8 hours in the presence of ZnO （mass fraction of 0.5%） as catalyst under the conditions of molar ratio of D,L-lactic acid, ethylene glycol and PDP 20 ： 1 ： 1, reaction temperature 160 ℃ and pressure 70 Pa.