广东地区肺癌多原发癌46例的外科疗效和预后分析

Surgical outcome and prognosis factor analysis for multiple primary lung cancers in Guangdong province

目的:探讨广东地区肺癌多原发癌(MPC)的诊治及其预后因素.方法:对1987-01/2003-09中山大学肿瘤防治中心收治肺癌MPC46例临床资料进行回顾性分析.结果:发生部位共97处,原发肺癌54处,头颈部28处,泌尿生殖系统7处,消化系统7处,其他1处,分别占55.7%,28.9%,7.2%,7.2%和1.0%.根治性手术组(CSR)与姑息治疗组(NCSR)的3a生存率分别为74%和21%,差异有统计学意义(P=0.000).结论:肺癌MPC应尽可能行根治性手术.

AIM： To study the diagnosis, treatment and prognostic factors of multiple primary lung cancers in Guangdong province. METHODS ： The clinical data of 46 cases of multiple primary lung cancers treated at cancer center of Sun Yat-Sen University from January 1987 to September 2003 were reviewed. RESULTS： Forty-six cases in this study had 97 malignant tumors, including lung cancer （n = 54 ）, head and neck cancer （ n = 28 ）, urogenital system cancer （ n = 7 ）, digestive system cancer 7, the other site 1. The incidents were 55.7%, 28.9%, 7.2%, 7.2% and 1.0% respectively. The 3-year survival rates were 74% and 21% respectively for the group of completely surgical resection and the group of non-completely surgical resection. The difference of survival rate was significant statistically （ P = 0.000）. CONCLUSION： Radical operation is the first choice for the patients of multiple primary lung cancers.