血浆脑钠尿肽及TIMI危险评分对急性心肌梗死患者的预后价值

Prognostic value of brain natriuretic peptide and TIMI risk score in patients with acute myocardial infarction

目的评估血浆脑钠尿肽(BNP)联合TIMI危险评分对急性心肌梗死(AMI)患者预后价值。方法集中检测连续收入院且随访资料齐全的63例AMI患者血浆BNP,按TIMI危险评分的多个临床资料分析记分,将患者分成不同的危险层次,分析患者BNP水平及TIMI危险评分与患者3个月随访期主要不良心血管事件发生的关系。结果15例复合心血管事件中BNP≥137 pg/ml者占11例,随着BNP水平增高,患者的主要心血管事件发生率也增多,且随着TIMI危险评分值增加而逐渐升高。结论BNP水平和TIMI危险评分越高,临床预后越差。

AIM To evaluate the prognostic value of the combination of brain natriuretic peptide （BNP） and thrombolysis in myocardial infarction （TIMI） risk scoring system in patients with acute myocardial infarction （AMI）. METHODS Centralized measurements of BNP were performed after admission in 63 consecutive patients with AMI. TIMI risk scores were calculated from clinical data and risk stratification of patients was conducted according to the scores. The relation of BNP and TIMI risk scores and major adverse cardiovascular events （MACE） from a 3-month follow up were analyzed. RESULTS 11 cases out of the 15 patients with cardiac events were distributed in patients with BNP level over 137 pg/ml. A- mong these high-risk patients, the incidence of MACE increased significantly with the rise of TIMI risk score. CONCLUSION The higher the BNP level and TIMI risk score, the worse the prognosis.