曲马朵与芬太尼联合用于骨科术后静脉镇痛的效果观察被引量：1

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摘要目的观察曲马朵与芬太尼联合静脉镇痛在骨科术后镇痛中的临床效果及不良反应。方法90例ASAⅠ-Ⅱ级的骨科下肢手术患者,随机分成三组,单纯曲马朵组、单纯芬太尼组、曲马朵和芬太尼联合组,术后行4,8,12,24,48h的VAS评分和镇静Ramsay评分,对不良反应发生情况进行比较,并监测镇痛前、镇痛后4,8,12,24,48h的MAP、HR、SpO2指标。结果4,8,12,24h的VAS评分单纯曲马朵组与单纯芬太尼组、曲马朵和芬太尼联合组比较差异有统计学意义(P<0.05),48h评分三组间比较差异无统计学意义(P>0.05),Ramsay评分三组患者在各个时间点比较差异无统计学意义(P>0.05)。不良反应的发生率在联合用药组最低,三组患者镇痛前后的呼吸、循环功能均稳定。结论曲马朵与芬太尼联合静脉镇痛用于骨科手术术后是安全有效的,是一种理想的镇痛方法。

作者陆群英王强黄迅方梅

机构地区江苏省常熟市第二人民医院麻醉科

出处《中国煤炭工业医学杂志》 2007年第3期280-281,共2页 Chinese Journal of Coal Industry Medicine

关键词曲马朵芬太尼镇痛骨科手术

分类号 R614.24 [医药卫生—麻醉学]

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