精制蝮蛇抗栓酶治疗周围血管病100例分析

Effect of AVATE-3 on Peripheral Vascular Diseases (100 Cases Report)

本文报道应用精制蝮蛇抗栓酶－３治疗周围血管疾病１００例的临床疗效分析及临床体会。本组男６３例，女３７例，年龄１４￣８２岁，平均４７．６岁。其中下肢深静脉血栓５２例，肢体动脉硬化闭塞症３４例，，四肢血栓闭塞性脉管炎７例，大动脉炎７例。作者主张大剂量冲击治疗，以每天静脉点滴３．０￣６．０Ｕ，２１￣３０天为一疗程。治疗总有效率９１．０％。

100 patients with peripheral vascular diseases were treated using Snake venom an-tithrombuctic enzyme-Ⅲ (SVATE-3). There were 63 mals and 37 femals with a mean age of 47. 6(14-82) years old. 52 of them had deep venous thrombosis of the lower extremities; 34 cases had peripheral arterial occlusive disease; 7 cases had Buerger disease; 7 cases had Takayasu disease. The present study suggested that intensive treatment using large dosage of SVATE-3 was more useful. Total effective rate was 91. 0%.