小儿呼吸机相关性肺炎病原菌检测及药敏分析

Study of the clininal feather and drug-sensitivity test in the children with Ventilator-associated pneumonia

目地探讨小儿呼吸机相关性肺炎的临床特征与病原菌的耐药情况、防治措施。方法分析54例小儿呼吸机相关性肺炎的临床特征与药敏试验结果。结果本组小儿呼吸机相关性肺炎的病原菌均为革兰氏阴性(G-)杆菌,其中铜绿假单胞菌23例(42.6%),大肠肝菌11例(20.4%),肺炎克雷伯氏杆菌11例(20.4%),其他假单胞菌(包括荧光假单胞菌、嗜麦芽假单胞菌)9例(16.7%),均对常用抗生素耐药,而对环丙沙星、亚胺培南、头孢他定等抗生素较敏感,敏感率达59.8%-85.2%。结论小儿呼吸机相关性肺炎的病原菌常为铜绿假单胞菌、大肠杆菌、肺炎克雷伯氏杆菌和其它假单胞菌,耐药率高,须积极防治。

Objective To investigate the clinical feather, the susceptibility tests of pathogenic bacteria, prevention and treatment therapy in children with Ventilator-asseciated pneumonia. Methods 54children were observed. Their clinical feather and drug-sensitivity test were evaluaded. Results pseudomonats aeruginsa. klebsiella pneumonia. Eacherichia coli were most common bacteria of Ventilator-asseciated pneumonia, and all were resistant to routin antibiotic, but were sensitivie to ciprofloxacin, ceflazidime, imipenem/cilastatim sodium. The sensitive rate was 59.8%-85.2%. Conclusions The neonate and inflant are most common age group of onset. It is difficult to differentiate pseudomonas pneumonia and serioual pneumonia resulted from familiar pathogens. The resistance rate in pseudomonas was high. Prevention and treatment were carried out.