摘要
联合应用尿激酶-丹参-肝素对体外血凝块进行溶解试验，测定溶解度和残留液中血红蛋白定量，观察血块中纤维蛋白降解情况。结果显示在设计的各实验组中，以血块形成72小时联合使用尿激酶-丹参-肝素处理24小时组溶解效果最佳，包括残留血块最轻，残留液中血红蛋白最高，病检中显示纤维蛋白降解最完全。说明联合应用尿激酶-丹参-肝素可以促进血凝块的溶解，且血凝块形成72小时后给药溶解效果最佳。从而为临床上选择治疗时机和拟订方案提供初步的实验依据。
The hematoma lysis in vitro was studied by the use of urokinase, Radix saliva miliorrhiza and heparin.The solubility of hematoma and the content of hemoglobin in residue solution were measured and the change of fibrinolysis in clot was observed. From the experiment, the effect of hematoma lysis was the best when we used UK +RSM+H for 24 hours after the formation of hematoma during 72 hours. It showed the lowest weight of residue clot and the highest content of hemoglobin in residue solution, and the fibrin was degradated completely under microscope. The result showed three drugs combined could accelerate the hematoma lysis and the effect of lysis was the best 72 hours after the formation of the clot. It offers the experimental evidence for time and plan of treatment of intracerebral hematoma.
出处
《急诊医学》
CSCD
1996年第3期139-141,共3页
关键词
尿激酶
丹参
颅内血肿
中西医结合治疗
Urokinase
Radix saliva miltiorrhiza
Heparin
Hypertension
Intracerebral hematoma
