9厂家牛黄解毒片中5种微量元素检测

Detection of the Contents of Five Trace Elements in Nine Niuhuang Jiedu Tablet Products

目的:测定牛黄解毒片中铬(Cr)、锰(Mn)、铁(Fe)、锌(Zn)、铜(Cu)5种微量元素的含量,以对其质量进行监控。方法:采用压力溶弹消解快速火焰原子吸收法对牛黄解毒片中的Cr、Mn、Fe、Zn、Cu5种微量元素含量进行测定。结果:9个不同厂家生产的牛黄解毒片中Cr、Mn、Zn、Cu含量相差不大,而Fe含量则有较大差异,且远高于其它元素的含量。结论:该方法简便快速、准确可靠,是一种适合本品常规分析的检测方法;本品不同品牌间各元素的含量差异很大,可能导致疗效有所差别。

OBJECTIVE： To detect the contents of five trace elements- chromium（Cr）, manganese（Mn）, iron（Fe）, zinc （Zn）, copper（Cu） in Niuhuang Jiedu tablets, and implement monitoring control over their quality. METHODS： The method of high pressure digestion - atomic flame absorption spectrometry was applied to detect the contents of the five trace elements in nine Niuhuang Jiedu Tablet products. RESULTS： There were insignificant differences in the contents of chromium（Cr）, manganese（Mn）, zinc（Zn）, copper（Cu） in the nine Niuhuang Jiedu Tablet products , but highly significant differences in the content of iron（Fe）, with the content of iron being far greater than those of other elements. CONCLUSIONS： This method is simple, rapid, accurate and reliable, and is a detection method for normal analysis of Niuhuang Jiedu Tablets.