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抗肿瘤新药——Combretastatin A4磷酸酯 被引量:5

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作者 张璇 张健存
出处 《中国药房》 CAS CSCD 北大核心 2007年第10期779-781,共3页 China Pharmacy
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参考文献20

  • 1Dark GG,Hill SA,Prise VE,et al.Combretastatin A-4,an agent that displays potent and selective toxicity toward tumor vasculature[J].Cancer Res,1997,57(10):1 829.
  • 2Tozer GM,Kanthou C,Baguley BC.Disrupting tumour blood vessels[J].Nat Rev Cancer,2005,5(6):423.
  • 3Kanthou C,Greco O,Stratford A,et al.The tubulin-binding agent combretastatin A-4-phosphate arrests endothelial cells in mitosis and induces mitotic cell death[J].Am J Pathol,2004,165(4):1 401.
  • 4Vincent L,Kermani P,Young LM,et al.Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling[J].J Clin Invest,2005,115(11):2 993.
  • 5Ahmed B,Van Eijk LI,Bouma-Ter SJC,et al.Vascular targeting effect of combretastatin A-4 phosphate dominates the inherent angiogenesis inhibitory activity[J].Int J Cancer,2003,105(1):20.
  • 6Dowlati A,Robertson K,Cooney M,et al.A phase Ⅰ pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single dose intravenous schedule in patients with advanced cancer[J].Cancer Res,2002,62(12):3 408.
  • 7Rustin GJ,Galbraith SM,Anderson H,et al.Phase Ⅰ clinical trial of weekly combretastatin A4 phosphate:clinical and pharmacokinetic results[J].J Clin Oncol,2003,21(15):2 815.
  • 8Galbraith SM,Maxwell RJ,Lodge MA,et al.Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging[J].J Clin Oncol,2003,21(15):2 831.
  • 9Stevenson JP,Rosen M,Sun W,et al.Phase Ⅰ trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer:magnetic resonance imaging evidence for altered tumor blood flow[J].J Clin Oncol,2003,21(23):4 428.
  • 10West CM,Price P.Combretastatin A4 phosphate[J].Anticancer Drugs,2004,15(3):179.

同被引文献13

  • 1杨兆琪,邱国福,粱淑彩,胡先明.肿瘤血管生成抑制剂CA-4的合成[J].中国现代应用药学,2005,22(3):210-211. 被引量:6
  • 2刘双喜,沈配倩.3,4,5-三甲氧基苄溴三苯基膦盐的合成[J].齐鲁药事,2007,26(2):107-109. 被引量:2
  • 3West CML, Price P. Combretastatin A4 phosphate [ J ]. Anti - Cancer Drugs, 2004,15 ( 3 ) : 179 - 187.
  • 4Lippert JW. Vascular disrupting agent [ J ]. Bioorg Med Chem, 2007,15(2) :605 -615.
  • 5陆榕 樊慧蓉 刘昌 等.风车子素A4磷酸盐的大鼠药动学研究.中草药,2006,37:147-149.
  • 6West CML, Price P. Combretastatin A4 phosphate [J]. Anti - Cancer Drugs, 2004,15 ( 3 ) : 179 - 187.
  • 7Lin CM, Ho HH, Pettit GR, et al. Antimitotic natural products combretastatin A -4 and combrestastatin A -2: studies on the mechanism of their ingibition of the binding of colchicine to tubulin[ J]. Biochemistry , 1989,28:6984 - 6991.
  • 8Lippert JW. Vascular disrup ting agent [J]. Bioorg Med Chem, 2007.15(2) :605 -615.
  • 9Lippert JW.Vascular disrupting agent[J].Bioorg Med Chem,2007,15(2):605-615.
  • 10牛犇,方素华,包旭,邱果,尹海林,包定元,王红星,徐小平.康普瑞丁磷酸二钠在体内外的抗肿瘤作用[J].华西药学杂志,2007,22(6):632-635. 被引量:2

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