乳腺癌术后及术后放疗引起上肢淋巴水肿的微波治疗

The microwave therapy for arm lymphedema of postoperative and radiotherapy of breast cancer

目的:探讨微波治疗乳癌手术及术后放疗引起上肢淋巴水肿的临床疗效。方法:对56例乳癌手术及术后放射治疗引起的上肢淋巴水肿患者采用微波治疗。结果:总缓解率100%;完全缓解率64.3%(36/56);部分缓解率30.4%(17/56),轻度缓解率3.6%(3/56)。轻/中度水肿缓解率100%(48/48);重度水肿缓解率62.5%(5/8)。单纯手术后水肿缓解率100%(29/29);术后放疗后水肿缓解率88.9%(24/27)。统计学分析,轻/中度淋巴水肿和重度淋巴水肿缓解率之间有显著性差异(P<0.01);单纯手术后淋巴水肿和术后加放疗淋巴水肿缓解率之间有显著性差异(P<0.01);术后放射治疗发生重度淋巴水肿患者无完全缓解病例。结论:微波治疗能使乳腺癌手术及术后放疗引起的上肢淋巴水肿减轻、消退,淋巴水肿程度愈轻疗效愈好,术后放疗且重度淋巴水肿患者疗效不佳。

Objective： To study the clinical efficacy of arm lymphedema induced by radical operation and postoperative radiotherapy of carcinoma of breast by microwave therapy. Methods： Fifty - six breast cancer .patients of arm lymphedema induced by radical operation and postoperative radiotherapy were treated with microwave. Results： Objective confirmed responses were observed in 56 patients （ 100% ）, including 36 complete responses （64.3 % ）and 17 partial responses（ 30.4% ） . The response rate of soft/moderate arm lymphedema and hard lymphedema was 100% （48/48） and 62.5% （ 5/8 ） , respectively. The arm lymphedema of single postoperative of breast cancer .was 100% （29/29; ） ;postoperative radiotherapy cancer patients was 88.9% （24/27）. There was obvious difference of response between soft/moderate and hard lymphedema（ P 〈0.01 ）as well as single postoperative and postoperative radiotherapy cancer patients;（ P 〈 0.01 ）. There was no any complete response case in the hard lymphedema of postoperative radiotherapy cancer patients. Conclusion： MiCrowave therapy can relieve the arm lympbedema of postoperative and radiotherapy of breast cancer,the more gentle of lymphedema,the more good efficacy is, postoperative radiotherapy of breast cancer with hard lymphedema got low response.