手术治疗162例基底细胞癌临床分析

Surgical treatment of basal cell carcinoma:a retrospective analysis of 162 patients

目的探讨基底细胞癌的一般发病规律、好发部位、常见复发部位和手术治疗的治愈率。方法对162例基底细胞癌患者分别采用不同术式治疗的情况进行回顾性分析。结果162例基底细胞癌中,年龄50岁以上者119例,占73.5%;肿瘤单发者156例,占96%。肿瘤好发部位依次是面颊、鼻部、头皮、躯干、口周、眼睑等。肿瘤复发率为6.3%(13/162),易复发部位依次为鼻部、口周,其次是眼睑、头皮。结论手术治疗基底细胞癌治愈率高,复发率低,仍应作为本病首选治疗方法。手术方式与疗效、复发间无明显相关性。

Objective To evaluate the onset rules, predilection sites, common relapse sites and surgical outcomes of basal cell carcinoma （ BCC ）. Methods A retrospective study was performed of 162 patients with basal cell carcinoma admitted to Institute of Dermatology, Chinese Academy of Medical Sciences ＆ Peking Union Medical College between 1987 and 2005. Results Of the 162 patients with basal cell carcinoma, 119 （ 73.5% ） were older than 50 years, 156 （ 96% ） had a solitary lesion. The most frequently affected sites, in descending order, were the cheek, nose, scalp, think, perioral, and eyelids. During the 1-3 year follow-up period, local recurrence occurred in 13 （ 6.3% ） patients. The recurrence sites included nose （ n = 7 ）, perioral （ n = 4 ）, eyelids （ n = 1 ）, and scalp （ n = 1 ）. Conclusions Surgical treatment is a highly effective treatment for basal cell carcinoma and should continue to be the treatment of choice in most cases. No significant correlation was observed between operation strategies and prognosis.