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PET代谢显像剂^11C-乙酸盐在临床中的应用 被引量：1

Clinical application of ^11C-acetate PET metabolism imaging
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摘要 ^18F-氟脱氧葡萄糖（^18F-FDG）是一种最常用的肿瘤正电子显像剂，但对于炎性病变鉴别困难，易得出肿瘤假阳性诊断结果。PET代谢显像剂^11C-乙酸能够弥补。^18F-FDGPET的某些不足，已用于各类肿瘤的诊断及鉴别诊断，特别是在肝癌以及前列腺癌等的诊断及鉴别诊断方面明显优于^18F-FDGPET；基于^11C-乙酸盐的特性，也常被用于心肌血流和灌注显像。 ^18F-fluorodeoxyglueose （^18F-FDG） is the most widely used PET agent for imaging tumors. However, ^18F-FDG PET showed a relatively high false positive rate when it is used to differentia the malignant and benign lesions. ^11C-aeetate metabolie PET may overcome some limitations of ^18F-FDG PET and has elinieal potentials. It has demonstrated advantages over ^18F-FDG PET in the tumors such as prostate cancer, hepatocellular carcinoma. Because of the metabolie characteristics of ^11C-acetate, it may be used to assess myoeardial viability, blood flow and peffusion.
作者 罗作明 吴华
机构地区 福建医科大学附属厦门市第一医院核医学科、闽南PET中心
出处 《国际放射医学核医学杂志》 2007年第1期25-27,共3页 International Journal of Radiation Medicine and Nuclear Medicine
关键词 乙酸盐类 前列腺肿瘤 肝肿瘤 心肌显像 体层摄影术 发射型计算机 对比研究 Acetates Prostatic neoplasms Liver neoplasms Myocardial imaging Tomography, emission-computed Comparative study
分类号 R73 [医药卫生—肿瘤]
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参考文献15

  • 1Fricke E, Machtens S, Hofmann M, et al. Positron emission tomography with ^11C-acetate and ^18F-FDG in prostate cancerpatients. Eur J Nucl Med Mol Imaging, 2003, 30(4):607- 611.
  • 2Sun KT, Yeatman LA, Buxton DB, et al. Simultaneous measurement of myocardial oxygen consumption and blood flow using [1-Carbon-11] acetate. J Nucl Med, 1998, 39(2): 272-280.
  • 3Sciacca RR, Akinboboye O, Chou RL, et al. Measurement of myocardial blood flow with PET using 1-^11C-acetate. J Nucl Med,2001, 42(1): 63-70.
  • 4Klein LJ, Visser FC, Knaapenl P, et al. Carbon-11-acetate as a tracer of myocardial oxygen consumption. Eur J Nucl Med,2001, 28(5): 651-668.
  • 5Wolpers HG, Burchert W, Van den Hoff J, et al. Assessment of myocardial viability by use of ^11C-acetate and positron emissiontomography. J Circular, 1997, 95(6): 1417-1424.
  • 6Ukkonen H, Knuuti J, Katoh C, et al. Use of [^11C]-acetate and[^15O] O2 PET for the assessment of myocardial oxygen utilization in patients with chronic myocardial infarction. Eur J Nucl Med,2001, 28(3): 334-339.
  • 7Gropler RJ, Gehman EM, Sampathkumaran K, et al. Comparisonof carbon-11-acetate with fluorine-18-fluorodeoxyglueose for delineating viable myoeardium by positron emission tomography. J Am Coll Cardiol, 1993, 22(6): 1587-1597.
  • 8叶任高.内科学．第五版[M].北京:人民卫生出版社,2001.429.
  • 9Khan MA, Combs CS, Brunt EM, et al. Positron emission tomography scanning in the evaluation of hepatocellular carcinoma. J Hepatol, 2000, 32(5): 792-797.
  • 10Ho CL, Yu SC, Yeung DW. ^11C- acetate PET imaging in hepatocellular carcinoma and other liver masses. J Nucl Med, 2003, 44(2): 213-221.

共引文献8

同被引文献11

  • 1霍力,周前,党永红,傅喆,卢朝辉,桑新亭.^(11)C-Acetate与^(18)FDG PET联合显像在肝脏肿瘤诊断中的作用[J].中国肿瘤,2007,16(3):184-186. 被引量：15
  • 2Ho CL,Chen S,Yeung DW,et al.Dual-tracer PET/CT imaging in evaluation of metastatic hepatocellular carinoma.J Nucl Med,2007,48(6):902-909.
  • 3王全师.PET/CT在肝癌诊断中的临床价值[J].现代消化及介入诊疗,10(1):19-20.
  • 4Ho CL,Yu SC,Yeung DW.^11C-acetate PET imaging in hepatocellular carinoma and other liver masses.J Nucl Med,2003,44 (2):213-221.
  • 5Park JW,Kim JH,Kim SK,et al.A prospective evaluation of 18F-FDG and ^11C-acetate PET/CT for detection of primary and metastatic hepatocellular carcinoma.J Nucl Med,2008,49(12):1912-1921.
  • 6Hwang KH,Choi DJ,Lee SY,et al.Evaluation of patients with hepatocellular carcinomas using[^11C]-acetate and[18F]FDG PET/CT:A preliminary study.Appl Radiat Isot,2009,67(7-8):1195-1198.
  • 7Yun M,Bang SH,Kim JW,et al.The importance of acetyl coenzyme A synthetase for ^11C-acetate uptake and cell survival in hepatocellular carcinoma.J Nucl Med,2009,50(8):1222-1228.
  • 8Ho CL,Yu SC,Yeung DW.^11C-acetale PET imaging in hepatocellular carcinoma and other liver amsses.J Nucl Med,2003,44(2):213-221.
  • 9桑新亭,杜顺达,毛一雷,卢欣,杨志英,霍力,钟守先,黄洁夫.两种正电子发射型计算机断层扫描显像对性质不明的肝脏占位的诊断[J].中华医学杂志,2007,87(44):3122-3124. 被引量：3
  • 10刘羽,尹吉林,王欣璐.^(11)C-乙酸盐PET/CT显像在肿瘤诊断中的显像原理与临床应用[J].中国临床医学影像杂志,2009,20(8):630-632. 被引量：7

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国际放射医学核医学杂志
2007年 第1期

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