摘要
^18F-氟脱氧葡萄糖(^18F-FDG)是一种最常用的肿瘤正电子显像剂,但对于炎性病变鉴别困难,易得出肿瘤假阳性诊断结果。PET代谢显像剂^11C-乙酸能够弥补。^18F-FDGPET的某些不足,已用于各类肿瘤的诊断及鉴别诊断,特别是在肝癌以及前列腺癌等的诊断及鉴别诊断方面明显优于^18F-FDGPET;基于^11C-乙酸盐的特性,也常被用于心肌血流和灌注显像。
^18F-fluorodeoxyglueose (^18F-FDG) is the most widely used PET agent for imaging tumors. However, ^18F-FDG PET showed a relatively high false positive rate when it is used to differentia the malignant and benign lesions. ^11C-aeetate metabolie PET may overcome some limitations of ^18F-FDG PET and has elinieal potentials. It has demonstrated advantages over ^18F-FDG PET in the tumors such as prostate cancer, hepatocellular carcinoma. Because of the metabolie characteristics of ^11C-acetate, it may be used to assess myoeardial viability, blood flow and peffusion.
出处
《国际放射医学核医学杂志》
2007年第1期25-27,共3页
International Journal of Radiation Medicine and Nuclear Medicine