摘要
为评价敏乐啶溶液治疗脂溢性脱发的效果，作者进行了临床观察。选择２５０例脂溢性脱发患者进行研究，分为二组，敏乐啶组１８６例，用敏乐啶溶液治疗；对比组６４例，用３％樟脑酊治疗。患者均为男性，年龄２６～６５岁，病程１～２６年。两组患者年龄、病程及脱发类型在统计学上无显著性差异。嘱患者每日搽药两次，共观察６个月。敏乐啶组１８６例中，基本痊愈５例，显效７６例，好转７８例，无效２７例，瘙痒消失１１２例，总有效率为８５．５％，止痒率６０．２％。对比组６４例中，无一例基本痊愈，显效９例，好转２５例，无效３０例，瘙痒消失３１例，总有效率５３．１％，止痒率４８．４％。不良反应发生率敏乐啶组１．１％，对比组４．７％，表现为轻度皮肤红斑及瘙痒。敏乐定溶液是治疗脂溢性脱发的有效药物，其疗效高于樟脑酊。
Inordertoevaluatetheefectofliquorminoxidiliintreatingmalepatternalopecia(MPA),aclinicalobservationwascarriedout.250patientswithMPAwereacceptedintheclinicalob-servation.Theywereseparatedintotwogroups.186patientswereassignedtominoxidilgroupandtreatedwithliquorminoxidli;64patientswereassignedtocontrolgroupandtreatedwith3%tincturacamphora.Althepatientsweremales,age26-65,durationofalopecia1～26years.Inbothgroups,therewereonsignificantdifferencesstatisticalyinages,sex,durationandalopeciaformsofthedis-ease.Eachpatientwasorderdtoapplythedruglocalytwiceeverydayandclinicalobsevationswerecarriedoutfor6months.Of186patientsinminoxidilgroup,5basicalycured,76markedimproved,78improved,27failedtorespond,112freedfromitching.Thetotalefectiveratewas85.5%andtheantipruriticratewas60.2%.Of64patientsincontrolgroup,nonebasicalycured,9markedim-proved,25improved,30failedtorespond,31freedfroomitching.Thetotaleffectiveratewas53.1%andtheantipruriticratewas48.4%.Theincidenceofside-efectsincludingslighterythemaandprurituswas1.1%inminoxidilgroupand4.7%incontrolgroup.TheresultsdemonstratethatliquorminoxidiliisthetreatmentofchoiceforMPA.LiquorminoxidiliisbetterthantincturacamphoraintreatingMPA.
