新生儿医原性高血糖症的预防

Study on Preventing Newborns from Iatrogenic Hyperglycemia

将40例新生儿随机分为两组,一组输入10%葡萄糖溶液(甲组),另一组输入5%葡萄糖溶液(乙组)。结果输液后1小时比输液后30分钟血糖值明显升高,输入2小时后血糖值下降,甲组患儿因输液速度较快(8～18滴/分)于输液后1小时血糖值升高显著,均超过正常值,且屎糖定性阳性,12例出现多尿。提示:新生儿静脉补液以5%葡萄糖溶液、速度低于8滴/分为宜,并注意观察尿量的变化,预防高血糖症的发生。

Fourty newborns were divided into two groups(group A 10% glucose infusion and group B 5% glucose infusion). The results showed that the concentration of blood sugar increased higher one hour after in fusion than 30 minutes after infusion and decreased two hours later. In group A,one hour after the infusion the level of blood glucose went up higher than the normal limits and glucose presented in the urine and 12 patients developed diuresis as a result of faster infusion speed (8～18 drops/min). Our study indicates that in order to prevent newborn from hyperglycenia when they receive glucose infusion,it is better to use 5% solution and at the rate of 8 drops per minute,and the output of urine should be observed carefully.