191株鲍氏不动杆菌耐药分析

Resistant analysis of 191 isolates of Acinetobacter Baumannii.

目的分析我院2004年8月至2006年11月间鲍氏不动杆菌感染的耐药状况,为临床治疗提供可靠依据。方法采用生物梅里埃公司的ATB expression系统进行细菌鉴定,K-B法进行药敏试验,用WHONET 5.3软件分析细菌的耐药性。结果鲍氏不动杆菌对碳青霉烯类抗生素的敏感率达93%以上,其他抗生素耐药严重,出现多重耐药和全耐药的鲍氏不动杆菌。结论治疗鲍氏不动杆菌感染必须依据药敏结果合理使用抗生素。

Objective To investigate resistance of acinetobacter baumannii in DaLian Friendship Hospital from August 2004 to November 2006, providing laboratory evidences for clinical treatment. Methods Acinetobacter banmannii was identified by ATB expression system （ bioM^rieux Corporate） and susceptibility was determined by Kirby - Bauer method. The resistance rates were analyzed by WHONET 5.3 software （ World Health Organization）. Results Over 93 % isolates of acinetobacter banmannii were sensitive to carbapenems, however, acinetobacter banmannii was severely resistant to many other antimicrobial agents. There were multi - drug resistant and pan - drug resistant strains of acinetobacter banmannii. Conclusion Reasonable use of antibiotics based on susceptibility test is needed.