输注血小板治疗32例流行性出血热的临床观察

Observation on 32 Patients with Epidemic Hemorrhagic Fever Treated by Thrombocyte Infusion

输注新鲜血小板治疗重型和危重型流行性出血热３２例，并与２２例作比较。结果显示，治疗组较对照组少尿持续时间平均缩短２．０３４天（Ｐ＜０．０５），颅内出血和肺出血发生率明显降低（Ｐ＜０．０５），病死率明显降低（Ｐ＜０．０５）。认为早期使用新鲜血小板，在预防出血、减轻症状等方面有较好疗效，对出血症状明显并伴血小板数量和功能明显降低者，应尽早输注血小板，以避免发生大出血。

patients with severe epidemic hemorrhagic fever were given fresh thrombocyte infusion,another 22 cases being controls.The results showed that the average duration of oliguria in infusion group patients was 2.034 days,shorter than that in controls(P<0.05);Developments of intracranial and lung hemorrhage were less in infusion group than that in controls(P<0.05),so was the mortality (P<0.05).It indicates fresh thrombocyte infusion in early stage of the disease is effective in preventing from hemorrhage and relieving symptoms.Thrombocyte infusion should be given as early as possible to those who have obvious bleeding and lower platelet counts and functions.In this way,severe hemorrhage can be avoided.