急性脑梗死患者认知功能障碍与病灶部位的相关性研究

Study of the related factors between location of cerebral infarction and cognitive impairment

目的探讨急性脑梗死患者的认知功能障碍与病灶部位的关系,为临床早期诊断和治疗认知功能障碍提供依据。方法对60例急性脑梗死患者利用韦氏成人智力量表(WAIS-RC)进行测查全量表智商(FIQ)后,将患者分为认知功能障碍组和非认知功能障碍对照组,选用磁共振成像进行病灶部位和范围的检测,评定患者的认知功能与病灶部位的相关性。结果急性脑梗死患者认知功能障碍的发生率为48．3%;两组患者大脑半球左侧和右侧、前部和后部、皮层和皮层下、大脑中动脉供血区和大脑后动脉供血区相比,有统计学差异(P＜0．05)。结论脑梗死患者的认知功能障碍与病灶部位具有相关性,大脑半球损伤左侧、前部、皮层更可能导致认知功能障碍。

Objective To evaluate the related factors between location of cerebral infarction and cognitive impairment. Methods Case-control study in hospital was taken in this study. 60 patients of first-time infarction lesions were assessed by WAIS-RC. The subjects were divided into 2 groups. All patients were studied with the same MRI scanner. Results The incidence of cognitive impairment was 48.3%. There were no significant differences between groups in gender, education and other disease. There was significant difference between patients with left-side and right-side cerebral infarction, anterior and posterior cerebral infarction. Conclusion Patients with left-side and anterior cerebral infarction,and cortical cerebral infarction tend to suffer from cognitive impairment. The location of damages in the area of middle cerebral artery tend to cause cognitive impairment.