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胰岛素信号传导与2型糖尿病 被引量：9

Insulin-signaling transmission and Type 2 Diabetes Mellitus
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摘要 胰岛素与其受体结合,通过一系列细胞内信号分子的作用,引起细胞内信号转导,最终到达效应器产生各种生理效应。胰岛素信号转导在胰岛素生理作用发挥中起着重要的作用。胰岛素信号转导障碍,使胰岛素生理作用减弱,导致胰岛素抵抗和2型糖尿病。 Insulin integrated with insulin receptor, after the functioning of signaling molecule in ceils, which resuits in signaling transmission within cells, effectors created physiological effect. Insuhn-signaling transmission plays a key role in insulin physiological function. The dysfunction of insulin-signaling transmission weakens insuhn physiological function, and leads to insulin resistance and T2DM.
作者 张敬芳 王光浩 吴勇 欧阳静萍
机构地区 荆门职业技术学院医学院 荆门市第二人民医院 武汉大学医学院病理生理学系
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2007年第6期693-696,共4页 China Journal of Modern Medicine
基金 国家自然科学基金资助项目 (No.30370673)
关键词 胰岛素 信号转导 2型糖尿病 insulin signaling transmission T2DM
分类号 R333 [医药卫生—人体生理学] R587.1 [医药卫生—内分泌]
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参考文献26

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二级参考文献12

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中国现代医学杂志
2007年 第6期

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